There may be a benefit in switching up probiotic strains consumed from bottle to bottle, including using spore biotics. With any probiotics, you want to see multiple strains, and that the specific strain is identified on the bottle. As research grows on the benefits of specific strains for specific conditions, varying your intake could prove beneficial for many health conditions. Best! 

I would say every time you finish a bottle, switch it up if you can. There is no hard and fast rule here, but the thinking is that until we can all know exactly what strains we need as individuals, getting a wide variety may be the best way to go. And be sure to eat plenty of fiber-rich foods to feed the good bacteria. Best!